PDZBase: a protein–protein interaction database for PDZ-domains

Summary: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein–protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residuebased diagrams including schematic secondary structure information (for individual complexes). Availability: http://icb.med.cornell.edu/services/pdz/start. Contact: [email protected].